Women Who Pioneered Change in the Fight Against Cancer: A Legacy of Discovery and Advocacy

In honour of Women’s Month, we celebrate the women whose groundbreaking contributions to cancer research, treatment, and advocacy have shaped the global fight against the disease. From scientific breakthroughs to public awareness campaigns, these women have left a lasting impact on cancer care and prevention.
Rosalind Franklin: Unlocking the Secrets of DNA
Rosalind Franklin’s pioneering work in X-ray crystallography provided the first clear images of DNA, leading to the discovery of its double-helix structure. While her research was overshadowed by Watson and Crick’s Nobel Prize-winning findings, Franklin’s contributions laid the foundation for modern genetics. Today, her work continues to influence studies on genetic mutations, including those linked to cancer, advancing our understanding of how DNA changes contribute to the disease.
Dr Jane Wright: A Chemotherapy Trailblazer
Dr Jane Wright revolutionised cancer treatment by developing combination chemotherapy, which targeted cancer cells throughout the body rather than focusing solely on localised tumours. As one of the first African American women in medicine, her research transformed cancer care, making chemotherapy a cornerstone of modern oncology. Her pioneering efforts saved countless lives and continue to shape treatment strategies today.
Mary-Claire King: Uncovering the BRCA1 Gene
In the 1990s, geneticist Mary-Claire King identified the BRCA1 gene, linking specific mutations to an increased risk of breast and ovarian cancer. Her groundbreaking discovery paved the way for genetic testing, enabling early detection and preventive measures for those at higher risk. King’s work remains instrumental in shaping personalised cancer prevention strategies and empowering individuals to take proactive steps in their healthcare.
Angelina Jolie: Raising Awareness for Genetic Testing
In 2013, actress and humanitarian Angelina Jolie made global headlines when she publicly shared her decision to undergo a preventative double mastectomy after testing positive for the BRCA1 gene mutation. Her openness sparked an international conversation about genetic testing, encouraging countless women to seek testing and consider preventive options. Jolie’s advocacy has helped normalise discussions about hereditary cancer risk, empowering women to make informed choices about their health.
Rose Lathrop: Championing Cancer Survivorship
A cancer survivor and advocate, Rose Lathrop dedicated her life to improving the quality of life for those who had completed treatment. Through her work with the American Cancer Society, she helped establish essential resources and support networks for survivors, highlighting the unique physical and emotional challenges they face. Lathrop’s efforts reinforced the importance of survivorship care, ensuring that patients receive ongoing support long after treatment ends.
A Lasting Legacy
The contributions of these remarkable women remind us that the fight against cancer is driven by both scientific innovation and compassionate advocacy. Their work continues to inspire researchers, doctors, and activists striving to improve cancer prevention, treatment, and survivorship care. As we celebrate Women’s Month, we honour their legacies and reaffirm our commitment to a future where cancer research and support are more accessible to all.
About Dr. Sharpe
Dr. Natalie Sharpe is an expert oncologist with over 20 years of experience, having trained and worked in some of the most prestigious medical institutions in the United States. Now a full-time physician with the Doctors Hospital team, she treats patients with all types of cancer. However, one of her primary passions remains the management of breast cancer, a field closely tied to her early research at Columbia University.